Regarding isoimmunization, which statement is correct?

Isoimmunization occurs when an Rh-negative mother is exposed to Rh-positive blood, typically from her fetus. This exposure can lead her immune system to develop antibodies against the Rh factor, which can affect future pregnancies. The correct statement indicates that isoimmunization can indeed be prevented with a RhoGAM injection, which is given during pregnancy and shortly after delivery if the baby is Rh-positive. RhoGAM contains Rh immunoglobulin that prevents the mother's immune system from producing antibodies against the Rh factor.

Preventing isoimmunization is crucial because once a mother is sensitized, subsequent Rh-positive pregnancies can lead to hemolytic disease of the newborn, which can be severe and life-threatening. Thus, administering RhoGAM effectively reduces the risk of the mother forming these antibodies, maintaining a healthy pregnancy and avoiding complications.

In contrast, the other statements do not accurately reflect how isoimmunization works. It is not limited to those with a positive Rh factor, as it specifically concerns Rh-negative mothers. There is a standard schedule for RhoGAM injections based on established guidelines, rather than requiring a different schedule for each pregnancy. Furthermore, while trauma can lead to exposure to fetal blood and increase the risk of isoimmun